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Pharmacokinetics and pharmacodynamics of repeat dosing of gabapentin in adult horses

BACKGROUND: The repeated administration of high doses of gabapentin may provide better analgesia in horses than current clinical protocols. HYPOTHESIS AND OBJECTIVES: Administration of gabapentin at 40 and 120 mg/kg PO q 12 h for 14 days will not alter serum biochemistry findings or cause adverse ef...

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Detalles Bibliográficos
Autores principales: Gold, Jenifer R., Grubb, Tamara L., Cox, Sherry, Malavasi, Lais, Villarino, Nicholas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965223/
https://www.ncbi.nlm.nih.gov/pubmed/35150014
http://dx.doi.org/10.1111/jvim.16386

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