Internalization of Muscle-Specific Kinase Is Increased by Agrin and Independent of Kinase-Activity, Lrp4 and Dynamin

Muscle-specific kinase (MuSK) is a receptor tyrosine kinase absolutely required for neuromuscular junction formation. MuSK is activated by binding of motor neuron-derived Agrin to low-density lipoprotein receptor related protein 4 (Lrp4), which forms a complex with MuSK. MuSK activation and downstre...

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Detalles Bibliográficos
Autores principales: Gemza, Anna, Barresi, Cinzia, Proemer, Jakob, Hatami, Jasmin, Lazaridis, Margarita, Herbst, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965242/
https://www.ncbi.nlm.nih.gov/pubmed/35370548
http://dx.doi.org/10.3389/fnmol.2022.780659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965242/
https://www.ncbi.nlm.nih.gov/pubmed/35370548
http://dx.doi.org/10.3389/fnmol.2022.780659

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