Beyond Genes: Inclusion of Alternative Splicing and Alternative Polyadenylation to Assess the Genetic Architecture of Predisposition to Voluntary Alcohol Consumption in Brain of the HXB/BXH Recombinant Inbred Rat Panel

Post transcriptional modifications of RNA are powerful mechanisms by which eukaryotes expand their genetic diversity. For instance, researchers estimate that most transcripts in humans undergo alternative splicing and alternative polyadenylation. These splicing events produce distinct RNA molecules,...

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Detalles Bibliográficos
Autores principales: Lusk, Ryan, Hoffman, Paula L., Mahaffey, Spencer, Rosean, Samuel, Smith, Harry, Silhavy, Jan, Pravenec, Michal, Tabakoff, Boris, Saba, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965255/
https://www.ncbi.nlm.nih.gov/pubmed/35368676
http://dx.doi.org/10.3389/fgene.2022.821026

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