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Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography

A 15‐year‐old Miniature Horse mare with persistently increased plasma calcium (total and ionized) and serum parathyroid hormone concentrations was presented for suspected primary hyperparathyroidism. Ultrasonography of the thyroid region identified an enlarged heterogeneous mass axial to the right t...

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Autores principales: Colmer, Sarah F., Wulster, Kathryn, Johnson, Amy L., Levine, David G., Underwood, Claire, Watkins, Trevor W., Van Eps, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965272/
https://www.ncbi.nlm.nih.gov/pubmed/35150016
http://dx.doi.org/10.1111/jvim.16390
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author Colmer, Sarah F.
Wulster, Kathryn
Johnson, Amy L.
Levine, David G.
Underwood, Claire
Watkins, Trevor W.
Van Eps, Andrew W.
author_facet Colmer, Sarah F.
Wulster, Kathryn
Johnson, Amy L.
Levine, David G.
Underwood, Claire
Watkins, Trevor W.
Van Eps, Andrew W.
author_sort Colmer, Sarah F.
collection PubMed
description A 15‐year‐old Miniature Horse mare with persistently increased plasma calcium (total and ionized) and serum parathyroid hormone concentrations was presented for suspected primary hyperparathyroidism. Ultrasonography of the thyroid region identified an enlarged heterogeneous mass axial to the right thyroid lobe suggestive of an enlarged parathyroid gland, which was further confirmed using sestamibi nuclear scintigraphy and 3‐phase computed tomography. Percutaneous ultrasound‐guided ethanol ablation of the mass, a method not previously described in the horse, was performed under general anesthesia resulting in rapid normalization of plasma ionized calcium and serum parathyroid hormone concentrations. Ablation of abnormal parathyroid gland tissue may be a suitable alternative to surgical resection in certain cases of primary hyperparathyroidism in the horse.
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spelling pubmed-89652722022-04-05 Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography Colmer, Sarah F. Wulster, Kathryn Johnson, Amy L. Levine, David G. Underwood, Claire Watkins, Trevor W. Van Eps, Andrew W. J Vet Intern Med EQUINE A 15‐year‐old Miniature Horse mare with persistently increased plasma calcium (total and ionized) and serum parathyroid hormone concentrations was presented for suspected primary hyperparathyroidism. Ultrasonography of the thyroid region identified an enlarged heterogeneous mass axial to the right thyroid lobe suggestive of an enlarged parathyroid gland, which was further confirmed using sestamibi nuclear scintigraphy and 3‐phase computed tomography. Percutaneous ultrasound‐guided ethanol ablation of the mass, a method not previously described in the horse, was performed under general anesthesia resulting in rapid normalization of plasma ionized calcium and serum parathyroid hormone concentrations. Ablation of abnormal parathyroid gland tissue may be a suitable alternative to surgical resection in certain cases of primary hyperparathyroidism in the horse. John Wiley & Sons, Inc. 2022-02-12 2022-03 /pmc/articles/PMC8965272/ /pubmed/35150016 http://dx.doi.org/10.1111/jvim.16390 Text en © 2022 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle EQUINE
Colmer, Sarah F.
Wulster, Kathryn
Johnson, Amy L.
Levine, David G.
Underwood, Claire
Watkins, Trevor W.
Van Eps, Andrew W.
Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography
title Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography
title_full Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography
title_fullStr Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography
title_full_unstemmed Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography
title_short Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography
title_sort treatment of primary hyperparathyroidism in a miniature horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography
topic EQUINE
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965272/
https://www.ncbi.nlm.nih.gov/pubmed/35150016
http://dx.doi.org/10.1111/jvim.16390
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