Cargando…

MiR-494-3p Upregulation Exacerbates Cerebral Ischemia Injury by Targeting Bhlhe40

PURPOSE: Cerebral ischemia is related to insufficient blood supply and is characterized by abnormal reactive oxygen species (ROS) production and cell apoptosis. Previous studies have revealed a key role for basic helix-loop-helix family member e40 (Bhlhe40) in oxidative stress and cell apoptosis. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Lingjiang, Ji, Dandan, Zhi, Feng, Fang, Yu, Zhu, Zigang, Ni, Tong, Zhu, Qin, Bao, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965425/ https://www.ncbi.nlm.nih.gov/pubmed/35352891 http://dx.doi.org/10.3349/ymj.2022.63.4.389

Ejemplares similares

Bhlhe40: Gatekeeper of the GC
por: Nutt, Stephen L., et al.
Publicado: (2021)

Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells
por: Asanoma, Kazuo, et al.
Publicado: (2019)

Upregulation of INHBA mediated by the transcription factor BHLHE40 promotes colon cancer cell proliferation and migration
por: Wang, Jianan, et al.
Publicado: (2022)

Promotion of colorectal cancer by transcription factor BHLHE40 involves upregulation of ADAM19 and KLF7
por: Sui, Yuan, et al.
Publicado: (2023)

Extract of Spatholobus suberctus Dunn ameliorates ischemia-induced injury by targeting miR-494
por: Song, Shiqing, et al.
Publicado: (2017)

Non-circadian aspects of BHLHE40 cellular function in cancer
por: Kiss, Zsofia, et al.
Publicado: (2020)

Compound 331 selectively induces glioma cell death by upregulating miR-494 and downregulating CDC20
por: Zhang, Lei, et al.
Publicado: (2015)

17β-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression
por: Feng, Dan-dan, et al.
Publicado: (2021)

Regulating the regulator: Bhlhe40 directly keeps IL-10 in check
por: Gabryšová, Leona, et al.
Publicado: (2018)

BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1
por: Zhang, Yufeng, et al.
Publicado: (2022)

Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation
por: Lin, Chih-Chung, et al.
Publicado: (2014)

Bhlhe40 differentially regulates the function and number of peroxisomes and mitochondria in myogenic cells
por: Chang, Hsuan Chia, et al.
Publicado: (2018)

Overcoming ABCB1-mediated multidrug resistance by transcription factor BHLHE40
por: Yin, Yongmei, et al.
Publicado: (2023)

The role of BHLHE40 in clinical features and prognosis value of PDAC by comprehensive analysis and in vitro validation
por: Liu, Chao, et al.
Publicado: (2023)

Functional elucidation of miR-494 in the tumorigenesis of nasopharyngeal carcinoma
por: Duan, Hong-Fang, et al.
Publicado: (2015)

Retraction: Extract of Spatholobus suberctus Dunn ameliorates ischemia-induced injury by targeting miR-494
Publicado: (2019)

Effects of propofol on cardiac function and miR-494 expression in rats with hepatic ischemia/reperfusion injury
por: Lv, Jie, et al.
Publicado: (2021)

The mechanism by which miR-494-3p regulates PGC1-α-mediated inhibition of mitophagy in cardiomyocytes and alleviation of myocardial ischemia—reperfusion injury
por: Mu, Ninghui, et al.
Publicado: (2023)

BHLHE40, a potential immune therapy target, regulated by FGD5-AS1/miR-15a-5p in pancreatic cancer
por: Qi, Wenxin, et al.
Publicado: (2023)

The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination
por: Yu, Fang, et al.
Publicado: (2018)

Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity
por: Jarjour, Nicholas N., et al.
Publicado: (2019)

Bhlhe40 function in activated B and T(FH) cells restrains the GC reaction and prevents lymphomagenesis
por: Rauschmeier, René, et al.
Publicado: (2021)

Steady-state memory-phenotype conventional CD4(+) T cells exacerbate autoimmune neuroinflammation in a bystander manner via the Bhlhe40/GM-CSF axis
por: Cho, Min-Ji, et al.
Publicado: (2023)

miR-494 Contributes to Estrogen Protection of Cardiomyocytes Against Oxidative Stress via Targeting (NF-κB) Repressing Factor
por: Tang, Zhi-Ping, et al.
Publicado: (2018)

Leishmania donovani resides in modified early endosomes by upregulating Rab5a expression via the downregulation of miR-494
por: Verma, Jitender Kumar, et al.
Publicado: (2017)

Ischemic postconditioning protects nonculprit coronary arteries against ischemia-reperfusion injury via downregulating miR-92a, miR-328 and miR-494
por: Wang, Jian, et al.
Publicado: (2022)

IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation
por: Lin, Chih-Chung, et al.
Publicado: (2016)

BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver
por: Tian, Jing, et al.
Publicado: (2018)

Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p
por: Gao, Ying, et al.
Publicado: (2022)

Linoleic Acid Upregulates Microrna-494 to Induce Quiescence in Colorectal Cancer
por: Ogata, Ruiko, et al.
Publicado: (2021)

LncRNA TUG1 regulates the development of ischemia-reperfusion mediated acute kidney injury through miR-494-3p/E-cadherin axis
por: Chen, Li, et al.
Publicado: (2021)

Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus
por: Hamilton, Kelly A., et al.
Publicado: (2018)

BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy
por: Salmon, Avery J., et al.
Publicado: (2022)

Cardiac-specific knockdown of Bhlhe40 attenuates angiotensin II (Ang II)-Induced atrial fibrillation in mice
por: Ren, Kai-Wen, et al.
Publicado: (2022)

Involvement of a Basic Helix-Loop-Helix Gene BHLHE40 in Specification of Chicken Retinal Pigment Epithelium
por: Kinuhata, Toshiki, et al.
Publicado: (2022)

In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40
por: Wu, Jennifer E., et al.
Publicado: (2023)

BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia
por: Mercado, Miguel A. B., et al.
Publicado: (2023)

Ubiquitin-Specific Protease 29 Exacerbates Cerebral Ischemia-Reperfusion Injury in Mice
por: Hou, Jia-Bao, et al.
Publicado: (2021)

BHLHE40 confers a pro-survival and pro-metastatic phenotype to breast cancer cells by modulating HBEGF secretion
por: Sethuraman, Aarti, et al.
Publicado: (2018)

Identification of BHLHE40 expression in peripheral blood mononuclear cells as a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma
por: Kunadirek, Pattapon, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2u3hh1jgcvbj1dkrpnj2ooghqv