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Characterisation of the Function of a SINE-VNTR-Alu Retrotransposon to Modulate Isoform Expression at the MAPT Locus

SINE-VNTR-Alu retrotransposons represent one class of transposable elements which contribute to the regulation and evolution of the primate genome and have the potential to be involved in genetic instability and disease progression. However, these polymorphic elements have not been extensively analy...

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Detalles Bibliográficos
Autores principales: Fröhlich, Alexander, Pfaff, Abigail L., Bubb, Vivien J., Koks, Sulev, Quinn, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965460/
https://www.ncbi.nlm.nih.gov/pubmed/35370538
http://dx.doi.org/10.3389/fnmol.2022.815695

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