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An engineered nano-liposome-human ACE2 decoy neutralizes SARS-CoV-2 Spike protein-induced inflammation in both murine and human macrophages

Rationale: Macrophages are the frontline immune cells in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Angiotensin-converting enzyme 2 (ACE2) serves as the binding receptor to SARS-CoV-2 Spike glycoprotein for fusion and internalization into the human host cells...

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Detalles Bibliográficos
Autores principales:	Satta, Sandro, Meng, Zhaojie, Hernandez, Rebecca, Cavallero, Susana, Zhou, Tong, Hsiai, Tzung K., Zhou, Changcheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965482/ https://www.ncbi.nlm.nih.gov/pubmed/35401811 http://dx.doi.org/10.7150/thno.66831

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