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From engineered heart tissue to cardiac organoid

The advent of human pluripotent stem cells (hPSCs) presented a new paradigm to employ hPSC-derived cardiomyocytes (hPSC-CMs) in drug screening and disease modeling. However, hPSC-CMs differentiated in conventional two-dimensional systems are structurally and functionally immature. Moreover, these di...

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Detalles Bibliográficos
Autores principales: Cho, Jaeyeaon, Lee, Hyein, Rah, Woongchan, Chang, Hyuk Jae, Yoon, Young-sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965483/
https://www.ncbi.nlm.nih.gov/pubmed/35401829
http://dx.doi.org/10.7150/thno.67661

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