Inhibitor screening using microarray identifies the high capacity of neutralizing antibodies to Spike variants in SARS-CoV-2 infection and vaccination

Rationale: Mutations of SARS-CoV-2, which is responsible for coronavirus disease 2019 (COVID-19), could impede drug development and reduce the efficacy of COVID-19 vaccines. Here, we developed a multiplexed Spike-ACE2 Inhibitor Screening (mSAIS) assay that can measure the neutralizing effect of anti...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomei, Zheng, Mei, Wang, Hongye, Zhou, Haijian, Liang, Te, Zhang, Jiahui, Ren, Jing, Peng, Huoying, Li, Siping, Bian, Haodong, Wei, Chundi, Yin, Shangqi, He, Chaonan, Han, Ying, Li, Minghui, Hou, Xuexin, Zhang, Jie, Xie, Liangzhi, Lv, Jing, Kan, Biao, Wang, Yajie, Yu, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965487/
https://www.ncbi.nlm.nih.gov/pubmed/35401825
http://dx.doi.org/10.7150/thno.67038

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