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Chemotherapy-induced adenosine A2B receptor expression mediates epigenetic regulation of pluripotency factors and promotes breast cancer stemness

Rationale: Triple-negative breast cancer (TNBC) is characterized by its unique molecular profile, aggressive nature and lack of targeted therapy. Chemotherapy induces expression of pluripotency factors and mediates an active induction of breast cancer stem cells (BCSCs) in TNBC, which potentiates th...

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Detalles Bibliográficos
Autores principales: Lan, Jie, Wei, Guangyao, Liu, Jia, Yang, Fan, Sun, Rong, Lu, Haiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965495/
https://www.ncbi.nlm.nih.gov/pubmed/35401817
http://dx.doi.org/10.7150/thno.70581