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SLC6A14 Impacts Cystic Fibrosis Lung Disease Severity via mTOR and Epithelial Repair Modulation

Cystic fibrosis (CF), due to pathogenic variants in CFTR gene, is associated with chronic infection/inflammation responsible for airway epithelium alteration and lung function decline. Modifier genes induce phenotype variability between people with CF (pwCF) carrying the same CFTR variants. Among th...

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Detalles Bibliográficos
Autores principales:	Mercier, Julia, Calmel, Claire, Mésinèle, Julie, Sutanto, Erika, Merabtene, Fatiha, Longchampt, Elisabeth, Sage, Edouard, Kicic, Anthony, Boëlle, Pierre-Yves, Corvol, Harriet, Ruffin, Manon, Guillot, Loïc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965518/ https://www.ncbi.nlm.nih.gov/pubmed/35372502 http://dx.doi.org/10.3389/fmolb.2022.850261

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