Cargando…

Vangl2, a Core Component of the WNT/PCP Pathway, Regulates Adult Hippocampal Neurogenesis and Age-Related Decline in Cognitive Flexibility

Decline in episodic memory is one of the hallmarks of aging and represents one of the most important health problems facing Western societies. A key structure in episodic memory is the hippocampal formation and the dentate gyrus in particular, as the continuous production of new dentate granule neur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koehl, Muriel, Ladevèze, Elodie, Montcouquiol, Mireille, Abrous, Djoher Nora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965557/ https://www.ncbi.nlm.nih.gov/pubmed/35370613 http://dx.doi.org/10.3389/fnagi.2022.844255

Ejemplares similares

Prenatal Stress Inhibits Hippocampal Neurogenesis but Spares Olfactory Bulb Neurogenesis
por: Belnoue, Laure, et al.
Publicado: (2013)

A Baldwin interpretation of adult hippocampal neurogenesis: from functional relevance to physiopathology
por: Abrous, Djoher Nora, et al.
Publicado: (2021)

Plasticity in the olfactory bulb of the maternal mouse is prevented by gestational stress
por: Belnoue, Laure, et al.
Publicado: (2016)

Inhibition of mTOR signaling by genetic removal of p70 S6 kinase 1 increases anxiety-like behavior in mice
por: Koehl, Muriel, et al.
Publicado: (2021)

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis
por: Dupret, David, et al.
Publicado: (2008)

Stem Cell Review Series: Role of neurogenesis in age-related memory disorders
por: Drapeau, Elodie, et al.
Publicado: (2008)

Retinoic Acid Restores Adult Hippocampal Neurogenesis and Reverses Spatial Memory Deficit in Vitamin A Deprived Rats
por: Bonnet, Emilie, et al.
Publicado: (2008)

Molecular Characterisation of Endogenous Vangl2/Vangl1 Heteromeric Protein Complexes
por: Belotti, Edwige, et al.
Publicado: (2012)

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis
por: Yates, Laura L., et al.
Publicado: (2010)

Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7–mediated Vangl ubiquitination and endoplasmic reticulum–associated degradation
por: Feng, Di, et al.
Publicado: (2021)

Gene-environment interaction in programming hippocampal plasticity: focus on adult neurogenesis
por: Koehl, Muriel
Publicado: (2015)

Sex-dependent effects of chronic exercise on cognitive flexibility but not hippocampal Bdnf in aging mice
por: Short, Annabel K., et al.
Publicado: (2022)

Age-related decline in cognitive flexibility is associated with the levels of hippocampal neurogenesis
por: Amelchenko, Evgeny M., et al.
Publicado: (2023)

Editorial: Hippocampal mechanisms in aging and clinical memory decline
por: Ginsberg, Stephen D., et al.
Publicado: (2023)

Role of Wnt Signaling in Adult Hippocampal Neurogenesis in Health and Disease
por: Arredondo, Sebastian B., et al.
Publicado: (2020)

Live imaging and conditional disruption of native PCP activity using endogenously tagged zebrafish sfGFP-Vangl2
por: Jussila, Maria, et al.
Publicado: (2022)

Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth
por: Dos-Santos Carvalho, Steve, et al.
Publicado: (2020)

The atypical Rho GTPase Rnd2 is critical for dentate granule neuron development and anxiety-like behavior during adult but not neonatal neurogenesis
por: Kerloch, Thomas, et al.
Publicado: (2021)

Enhanced hippocampal neurogenesis mediated by PGC-1α-activated OXPHOS after neonatal low-dose Propofol exposure
por: Chen, Keyu, et al.
Publicado: (2022)

Vangl2 in the Dentate Network Modulates Pattern Separation and Pattern Completion
por: Robert, Benjamin J.A., et al.
Publicado: (2020)

Wnt signaling in the regulation of adult hippocampal neurogenesis
por: Varela-Nallar, Lorena, et al.
Publicado: (2013)

Hippocampal Mitochondrial Transplantation Alleviates Age-Associated Cognitive Decline via Enhancing Wnt Signaling and Neurogenesis
por: Zhang, Zhaoyichun, et al.
Publicado: (2022)

The core PCP protein Prickle2 regulates axon number and AIS maturation by binding to AnkG and modulating microtubule bundling
por: Dorrego-Rivas, Ana, et al.
Publicado: (2022)

Age-Dependent Decline in Salinity Tolerance in a Euryhaline Fish
por: Inokuchi, Mayu, et al.
Publicado: (2021)

Effects of maternal diabetes on the Wnt-PCP pathway and embryogenesis
Publicado: (2015)

Preliminary findings of accelerated visual memory decline and baseline brain correlates in middle-age and older adults with autism: The case for hippocampal free-water
por: Walsh, Melissa J. M., et al.
Publicado: (2022)

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline
por: Cho, Kyung-Ok, et al.
Publicado: (2015)

AMPK Signaling Regulates the Age-Related Decline of Hippocampal Neurogenesis
por: Wang, Brian Z, et al.
Publicado: (2019)

Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons
por: Dupret, David, et al.
Publicado: (2007)

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates
por: Mattes, Benjamin, et al.
Publicado: (2018)

IRE-1 endoribonuclease activity declines early in C. elegans adulthood and is not rescued by reduced reproduction
por: De-Souza, Evandro A., et al.
Publicado: (2022)

The role of WNT and IL-1 signaling in osteoarthritis: therapeutic implications for platelet-rich plasma therapy
por: Tonutti, Antonio, et al.
Publicado: (2023)

Vangl as a Master Scaffold for Wnt/Planar Cell Polarity Signaling in Development and Disease
por: Dreyer, Courtney A., et al.
Publicado: (2022)

A Conceptual View of Cognitive Intervention in Older Adults With and Without Cognitive Decline—A Systemic Review
por: Mendes, Liliana, et al.
Publicado: (2022)

Responsiveness of dentate neurons generated throughout adult life is associated with resilience to cognitive aging
por: Montaron, Marie‐Françoise, et al.
Publicado: (2020)

Genetic analysis of Wnt/PCP genes in neural tube defects
por: Chen, Zhongzhong, et al.
Publicado: (2018)

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil
por: Sellers, Katherine J., et al.
Publicado: (2018)

The Drosophila Homologue of the Amyloid Precursor Protein Is a Conserved Modulator of Wnt PCP Signaling
por: Soldano, Alessia, et al.
Publicado: (2013)

Prescription Medications and Co-Morbidities in Late Middle-Age are Associated with Greater Cognitive Declines: Results from WRAP
por: Du, Lianlian, et al.
Publicado: (2022)

Living alone reduces the decline of calf circumference among Chinese older adults: A 4-year longitudinal study
por: Wang, Dong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m61td9bdgqgfrilsgnvb23cmu4