Cargando…

Pan-retroviral Nucleocapsid-Mediated Phase Separation Regulates Genomic RNA Positioning and Trafficking

The duality of liquid-liquid phase separation (LLPS) of cellular components into membraneless organelles defines the nucleation of both normal and disease processes including stress granule (SG) assembly. From mounting evidence of LLPS utility by viruses, we discover that HIV-1 nucleocapsid (NC) pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Monette, Anne, Niu, Meijuan, Chen, Lois, Rao, Shringar, James Gorelick, Robert, John Mouland, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965748/ https://www.ncbi.nlm.nih.gov/pubmed/32320662 http://dx.doi.org/10.1016/j.celrep.2020.03.084

Ejemplares similares

Zinc and Copper Ions Differentially Regulate Prion-Like Phase Separation Dynamics of Pan-Virus Nucleocapsid Biomolecular Condensates
por: Monette, Anne, et al.
Publicado: (2020)

6(th )International Symposium on Retroviral Nucleocapsid
por: Berkhout, Ben, et al.
Publicado: (2008)

The RNA surveillance proteins UPF1, UPF2 and SMG6 affect HIV-1 reactivation at a post-transcriptional level
por: Rao, Shringar, et al.
Publicado: (2018)

HIV-1 requires Staufen1 to dissociate stress granules and to produce infectious viral particles
por: Rao, Shringar, et al.
Publicado: (2019)

Host mRNA decay proteins influence HIV-1 replication and viral gene expression in primary monocyte-derived macrophages
por: Rao, Shringar, et al.
Publicado: (2019)

Liquid-liquid phase separation of nucleocapsid proteins during SARS-CoV-2 and HIV-1 replication
por: Chau, Bao-An, et al.
Publicado: (2023)

Implications of the Nucleocapsid and the Microenvironment in Retroviral Reverse Transcription
por: Mougel, Marylène, et al.
Publicado: (2010)

Retroviral nucleocapsid proteins and DNA strand transfers
por: René, Brigitte, et al.
Publicado: (2018)

Retrospective on the all-in-one retroviral nucleocapsid protein
por: Darlix, Jean-Luc, et al.
Publicado: (2014)

Trafficking of Sendai Virus Nucleocapsids Is Mediated by Intracellular Vesicles
por: Chambers, Raychel, et al.
Publicado: (2010)

Differential contribution of basic residues to HIV-1 nucleocapsid protein’s nucleic acid chaperone function and retroviral replication
por: Wu, Hao, et al.
Publicado: (2014)

Trafficking motifs in the SARS-coronavirus nucleocapsid protein
por: You, Jae-Hwan, et al.
Publicado: (2007)

Retroviral Env Glycoprotein Trafficking and Incorporation into Virions
por: Murakami, Tsutomu
Publicado: (2012)

T Lymphocytes as Measurable Targets of Protection and Vaccination Against Viral Disorders
por: Monette, Anne, et al.
Publicado: (2019)

Introduction to Special Issue “The 11th International Retroviral Nucleocapsid and Assembly Symposium”
por: Williams, Mark C., et al.
Publicado: (2020)

Back to the Roots: Noncanonical Retrograde Trafficking of the HBV Nucleocapsids
por: Bender, Daniela, et al.
Publicado: (2022)

Dual functions of the SARS-CoV-2 nucleocapsid domains mediate RNA binding and phase separation
por: Estelle, Aidan B., et al.
Publicado: (2023)

The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease during Maturation
por: Lyonnais, Sébastien, et al.
Publicado: (2021)

HIV-1 NC-induced stress granule assembly and translation arrest are inhibited by the dsRNA binding protein Staufen1
por: Rao, Shringar, et al.
Publicado: (2018)

HIV-1 remodels the nuclear pore complex
por: Monette, Anne, et al.
Publicado: (2011)

Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate
por: Iserman, Christiane, et al.
Publicado: (2020)

Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA
por: Chen, Hui, et al.
Publicado: (2020)

Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid
por: Iserman, Christiane, et al.
Publicado: (2020)

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA
por: Cubuk, Jasmine, et al.
Publicado: (2021)

Phase separation by the SARS-CoV-2 nucleocapsid protein: Consensus and open questions
por: Cascarina, Sean M., et al.
Publicado: (2022)

Phase separation underlies interactions of the SARS-CoV-2 nucleocapsid protein with nucleoli
por: Dogra, Priyanka, et al.
Publicado: (2023)

SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs
por: Perdikari, Theodora Myrto, et al.
Publicado: (2020)

Investigating retroviral super-infection in wild chimpanzees (Pan troglodytes verus)
por: Blasse, Anja, et al.
Publicado: (2011)

A Retrotranslocation Assay That Predicts Defective VCP/p97-Mediated Trafficking of a Retroviral Signal Peptide
por: Das, Poulami, et al.
Publicado: (2022)

Applications of RNA structure analysis to retroviral packaging and anti-retroviral therapeutic discovery
por: Weeks, Kevin M, et al.
Publicado: (2011)

Application of Live-Cell RNA Imaging Techniques to the Study of Retroviral RNA Trafficking
por: Bann, Darrin V., et al.
Publicado: (2012)

Nuclear Trafficking of Retroviral RNAs and Gag Proteins during Late Steps of Replication
por: Stake, Matthew S., et al.
Publicado: (2013)

Post-translational modifications of hnRNP A1 differentially modulate retroviral IRES-mediated translation initiation
por: Barrera, Aldo, et al.
Publicado: (2020)

The retrovirus RNA trafficking granule: from birth to maturity
por: Cochrane, Alan W, et al.
Publicado: (2006)

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates
por: Savastano, Adriana, et al.
Publicado: (2020)

Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly
por: Guseva, Serafima, et al.
Publicado: (2020)

A review of the effects of ATP and hydroxychloroquine on the phase separation of the SARS-CoV-2 nucleocapsid protein
por: Dang, Mei, et al.
Publicado: (2022)

Correction to ‘The double-stranded RNA-binding protein, Staufen1, is an IRES-transacting factor regulating HIV-1 cap-independent translation initiation’
por: Ramos, Hade, et al.
Publicado: (2021)

The double-stranded RNA-binding protein, Staufen1, is an IRES-transacting factor regulating HIV-1 cap-independent translation initiation
por: Ramos, Hade, et al.
Publicado: (2021)

A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions
por: Vercruysse, Thomas, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_r66p20buhq6qfr8mfau469tiue