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CYP2D6 gene resequencing in the Malagasy, a population at the crossroads between Asia and Africa: a pilot study

BACKGROUND: Plasmodium vivax malaria is endemic in Madagascar, where populations have genetic inheritance from Southeast Asia and East Africa. Primaquine, a drug of choice for vivax malaria, is metabolized principally via CYP2D6. CYP2D6 variation was characterized by locus-specific gene sequencing a...

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Detalles Bibliográficos
Autores principales:	Chan, E Ricky, Mehlotra, Rajeev K, Pirani, Karim A, Ratsimbasoa, Arsene C, Williams, Scott M, Gaedigk, Andrea, Zimmerman, Peter A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Medicine Ltd 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965795/ https://www.ncbi.nlm.nih.gov/pubmed/35230160 http://dx.doi.org/10.2217/pgs-2021-0146

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