Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India

BACKGROUND: Anorectal melanoma (AM) is a rare subtype of melanoma. AIM: To study the clinic–pathologic features and outcomes in patients with AM. MATERIALS & METHODS: Clinical, pathologic findings and outcomes of patients with AM were recorded. RESULTS: Twenty-seven patients with AM were identif...

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Detalles Bibliográficos
Autores principales: Garg, Vikas, Rastogi, Sameer, Aswar, Harshal, Shamim, Shamim A, Dhamija, Ekta, Barwad, Adarsh, Pandey, Rambha, Panwar, Rajesh, Upadhyay, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965809/
https://www.ncbi.nlm.nih.gov/pubmed/35369276
http://dx.doi.org/10.2144/fsoa-2021-0091
Descripción
Sumario:BACKGROUND: Anorectal melanoma (AM) is a rare subtype of melanoma. AIM: To study the clinic–pathologic features and outcomes in patients with AM. MATERIALS & METHODS: Clinical, pathologic findings and outcomes of patients with AM were recorded. RESULTS: Twenty-seven patients with AM were identified with median age of 57 years. Most patients presented in stage III (44.4%). Lymph node involvement was seen in 70.4%. The response to chemotherapy and immunotherapy was 16.6 and 25.0%, respectively. At a median follow up of 11 months, median overall survival was 30 months. Ballantine stage 3 and weight loss at presentation were predictors of poor survival. CONCLUSION: AM presents at an advanced stage with lymph node and distant metastasis.

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