Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India

BACKGROUND: Anorectal melanoma (AM) is a rare subtype of melanoma. AIM: To study the clinic–pathologic features and outcomes in patients with AM. MATERIALS & METHODS: Clinical, pathologic findings and outcomes of patients with AM were recorded. RESULTS: Twenty-seven patients with AM were identif...

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Autores principales: Garg, Vikas, Rastogi, Sameer, Aswar, Harshal, Shamim, Shamim A, Dhamija, Ekta, Barwad, Adarsh, Pandey, Rambha, Panwar, Rajesh, Upadhyay, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965809/
https://www.ncbi.nlm.nih.gov/pubmed/35369276
http://dx.doi.org/10.2144/fsoa-2021-0091
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author Garg, Vikas
Rastogi, Sameer
Aswar, Harshal
Shamim, Shamim A
Dhamija, Ekta
Barwad, Adarsh
Pandey, Rambha
Panwar, Rajesh
Upadhyay, Ashish
author_facet Garg, Vikas
Rastogi, Sameer
Aswar, Harshal
Shamim, Shamim A
Dhamija, Ekta
Barwad, Adarsh
Pandey, Rambha
Panwar, Rajesh
Upadhyay, Ashish
author_sort Garg, Vikas
collection PubMed
description BACKGROUND: Anorectal melanoma (AM) is a rare subtype of melanoma. AIM: To study the clinic–pathologic features and outcomes in patients with AM. MATERIALS & METHODS: Clinical, pathologic findings and outcomes of patients with AM were recorded. RESULTS: Twenty-seven patients with AM were identified with median age of 57 years. Most patients presented in stage III (44.4%). Lymph node involvement was seen in 70.4%. The response to chemotherapy and immunotherapy was 16.6 and 25.0%, respectively. At a median follow up of 11 months, median overall survival was 30 months. Ballantine stage 3 and weight loss at presentation were predictors of poor survival. CONCLUSION: AM presents at an advanced stage with lymph node and distant metastasis.
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spelling pubmed-89658092022-03-31 Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India Garg, Vikas Rastogi, Sameer Aswar, Harshal Shamim, Shamim A Dhamija, Ekta Barwad, Adarsh Pandey, Rambha Panwar, Rajesh Upadhyay, Ashish Future Sci OA Short Communication BACKGROUND: Anorectal melanoma (AM) is a rare subtype of melanoma. AIM: To study the clinic–pathologic features and outcomes in patients with AM. MATERIALS & METHODS: Clinical, pathologic findings and outcomes of patients with AM were recorded. RESULTS: Twenty-seven patients with AM were identified with median age of 57 years. Most patients presented in stage III (44.4%). Lymph node involvement was seen in 70.4%. The response to chemotherapy and immunotherapy was 16.6 and 25.0%, respectively. At a median follow up of 11 months, median overall survival was 30 months. Ballantine stage 3 and weight loss at presentation were predictors of poor survival. CONCLUSION: AM presents at an advanced stage with lymph node and distant metastasis. Future Science Ltd 2022-02-10 /pmc/articles/PMC8965809/ /pubmed/35369276 http://dx.doi.org/10.2144/fsoa-2021-0091 Text en © 2022 Dr. Sameer Rastogi https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Short Communication
Garg, Vikas
Rastogi, Sameer
Aswar, Harshal
Shamim, Shamim A
Dhamija, Ekta
Barwad, Adarsh
Pandey, Rambha
Panwar, Rajesh
Upadhyay, Ashish
Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India
title Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India
title_full Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India
title_fullStr Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India
title_full_unstemmed Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India
title_short Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India
title_sort clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in india
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965809/
https://www.ncbi.nlm.nih.gov/pubmed/35369276
http://dx.doi.org/10.2144/fsoa-2021-0091
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