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Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A “Sniffing Impairment” Influencing Refeeding?

Medications for general anesthesia can cause smell alterations after surgery, with inhalation anesthetics being the most acknowledged drugs. However, spine patients have been poorly studied in past investigations and whether these alterations could influence the refeeding remains unclear. This resea...

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Autores principales: Briguglio, Matteo, Crespi, Tiziano, Langella, Francesco, Riso, Patrizia, Porrini, Marisa, Scaramuzzo, Laura, Bassani, Roberto, Brayda-Bruno, Marco, Berjano, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965841/
https://www.ncbi.nlm.nih.gov/pubmed/35372489
http://dx.doi.org/10.3389/fsurg.2022.785676
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author Briguglio, Matteo
Crespi, Tiziano
Langella, Francesco
Riso, Patrizia
Porrini, Marisa
Scaramuzzo, Laura
Bassani, Roberto
Brayda-Bruno, Marco
Berjano, Pedro
author_facet Briguglio, Matteo
Crespi, Tiziano
Langella, Francesco
Riso, Patrizia
Porrini, Marisa
Scaramuzzo, Laura
Bassani, Roberto
Brayda-Bruno, Marco
Berjano, Pedro
author_sort Briguglio, Matteo
collection PubMed
description Medications for general anesthesia can cause smell alterations after surgery, with inhalation anesthetics being the most acknowledged drugs. However, spine patients have been poorly studied in past investigations and whether these alterations could influence the refeeding remains unclear. This research aims to observe detectable dysosmias after spine surgery, to explore any amplified affection of halogenates (DESflurane and SEVoflurane) against total intravenous anesthesia (TIVA), and to spot potential repercussions on the refeeding. Fifty patients between 50 and 85 years old were recruited before elective spine procedure and tested for odor acuity and discrimination using the Sniffin' Sticks test. The odor abilities were re-assessed within the first 15 h after surgery together with the monitoring of food intakes. The threshold reduced from 4.92 ± 1.61 to 4.81 ± 1.64 (p = 0.237) and the discrimination ability reduced from 10.50 ± 1.83 to 9.52 ± 1.98 (p = 0.0005). Anesthetic-specific analysis showed a significant reduction of both threshold (p = 0.004) and discrimination (p = 0.004) in the SEV group, and a significant reduction of discrimination abilities (p = 0.016) in the DES group. No dysosmias were observed in TIVA patients after surgery. Food intakes were lower in the TIVA group compared to both DES (p = 0.026) and SEV (p = 0.017). The food consumed was not associated with the sniffing impairment but appeared to be inversely associated with the surgical time. These results confirmed the evidence on inhalation anesthetics to cause smell alterations in spine patients. Furthermore, the poor early oral intake after complex procedures suggests that spinal deformity surgery could be a practical challenge to early oral nutrition.
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spelling pubmed-89658412022-03-31 Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A “Sniffing Impairment” Influencing Refeeding? Briguglio, Matteo Crespi, Tiziano Langella, Francesco Riso, Patrizia Porrini, Marisa Scaramuzzo, Laura Bassani, Roberto Brayda-Bruno, Marco Berjano, Pedro Front Surg Surgery Medications for general anesthesia can cause smell alterations after surgery, with inhalation anesthetics being the most acknowledged drugs. However, spine patients have been poorly studied in past investigations and whether these alterations could influence the refeeding remains unclear. This research aims to observe detectable dysosmias after spine surgery, to explore any amplified affection of halogenates (DESflurane and SEVoflurane) against total intravenous anesthesia (TIVA), and to spot potential repercussions on the refeeding. Fifty patients between 50 and 85 years old were recruited before elective spine procedure and tested for odor acuity and discrimination using the Sniffin' Sticks test. The odor abilities were re-assessed within the first 15 h after surgery together with the monitoring of food intakes. The threshold reduced from 4.92 ± 1.61 to 4.81 ± 1.64 (p = 0.237) and the discrimination ability reduced from 10.50 ± 1.83 to 9.52 ± 1.98 (p = 0.0005). Anesthetic-specific analysis showed a significant reduction of both threshold (p = 0.004) and discrimination (p = 0.004) in the SEV group, and a significant reduction of discrimination abilities (p = 0.016) in the DES group. No dysosmias were observed in TIVA patients after surgery. Food intakes were lower in the TIVA group compared to both DES (p = 0.026) and SEV (p = 0.017). The food consumed was not associated with the sniffing impairment but appeared to be inversely associated with the surgical time. These results confirmed the evidence on inhalation anesthetics to cause smell alterations in spine patients. Furthermore, the poor early oral intake after complex procedures suggests that spinal deformity surgery could be a practical challenge to early oral nutrition. Frontiers Media S.A. 2022-03-16 /pmc/articles/PMC8965841/ /pubmed/35372489 http://dx.doi.org/10.3389/fsurg.2022.785676 Text en Copyright © 2022 Briguglio, Crespi, Langella, Riso, Porrini, Scaramuzzo, Bassani, Brayda-Bruno and Berjano. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Briguglio, Matteo
Crespi, Tiziano
Langella, Francesco
Riso, Patrizia
Porrini, Marisa
Scaramuzzo, Laura
Bassani, Roberto
Brayda-Bruno, Marco
Berjano, Pedro
Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A “Sniffing Impairment” Influencing Refeeding?
title Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A “Sniffing Impairment” Influencing Refeeding?
title_full Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A “Sniffing Impairment” Influencing Refeeding?
title_fullStr Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A “Sniffing Impairment” Influencing Refeeding?
title_full_unstemmed Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A “Sniffing Impairment” Influencing Refeeding?
title_short Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A “Sniffing Impairment” Influencing Refeeding?
title_sort perioperative anesthesia and acute smell alterations in spine surgery: a “sniffing impairment” influencing refeeding?
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965841/
https://www.ncbi.nlm.nih.gov/pubmed/35372489
http://dx.doi.org/10.3389/fsurg.2022.785676
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