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Computational analysis of cortical neuronal excitotoxicity in a large animal model of neonatal brain injury
BACKGROUND: Neonatal hypoxic brain injury is a major cause of intellectual and developmental disability. Hypoxia causes neuronal dysfunction and death in the developing cerebral cortex due to excitotoxic Ca(2+)-influx. In the translational piglet model of hypoxic encephalopathy, we have previously s...
Autores principales: | Kratimenos, Panagiotis, Vij, Abhya, Vidva, Robinson, Koutroulis, Ioannis, Delivoria-Papadopoulos, Maria, Gallo, Vittorio, Sathyanesan, Aaron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966144/ https://www.ncbi.nlm.nih.gov/pubmed/35351004 http://dx.doi.org/10.1186/s11689-022-09431-3 |
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