KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis

BACKGROUND: Frequent truncation mutations of the histone lysine N-methyltransferase KMT2C have been detected by whole exome sequencing studies in various cancers, including malignancies of the prostate. However, the biological consequences of these alterations in prostate cancer have not yet been el...

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Detalles Bibliográficos
Autores principales: Limberger, Tanja, Schlederer, Michaela, Trachtová, Karolina, Garces de los Fayos Alonso, Ines, Yang, Jiaye, Högler, Sandra, Sternberg, Christina, Bystry, Vojtech, Oppelt, Jan, Tichý, Boris, Schmeidl, Margit, Kodajova, Petra, Jäger, Anton, Neubauer, Heidi A., Oberhuber, Monika, Schmalzbauer, Belinda S., Pospisilova, Sarka, Dolznig, Helmut, Wadsak, Wolfgang, Culig, Zoran, Turner, Suzanne D., Egger, Gerda, Lagger, Sabine, Kenner, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966196/
https://www.ncbi.nlm.nih.gov/pubmed/35354467
http://dx.doi.org/10.1186/s12943-022-01542-8

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