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Mechanistic Clues Provided by Concurrent Changes in the Expression of Genes Encoding the M(1) Muscarinic Receptor, β-Catenin Signaling Proteins, and Downstream Targets in Adenocarcinomas of the Colon

Muscarinic receptors (MRs) in the G protein-coupled receptor superfamily are recipients and mediators of parasympathetic neural transmission within the central and enteric nervous systems. MR subtypes, M(1)R–M(5)R, encoded by CHRM1-CHRM5, expressed widely throughout the gastrointestinal (GI) tract,...

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Detalles Bibliográficos
Autores principales: Alizadeh, Madeline, Schledwitz, Alyssa, Cheng, Kunrong, Raufman, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966224/
https://www.ncbi.nlm.nih.gov/pubmed/35370785
http://dx.doi.org/10.3389/fphys.2022.857563