o-Aminoazotoluene, 7,12-dimethylbenz[a]anthracene, and N-ethyl-N-nitrosourea, which are mutagenic but not carcinogenic in the colon, rapidly induce colonic tumors in mice with dextran sulfate sodium-induced colitis

BACKGROUND: Several rodent models with chemically induced colon cancer have been developed. Among these models, dextran sulfate sodium (DSS), a colitis inducer, combined with azoxymethane as a colon mutagenic carcinogen, is commonly used. We previously reported that although benzo [a] pyrene (BP) is...

Descripción completa

Detalles Bibliográficos
Autores principales: Hakura, Atsushi, Koyama, Naoki, Seki, Yuki, Sonoda, Jiro, Asakura, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966303/
https://www.ncbi.nlm.nih.gov/pubmed/35351212
http://dx.doi.org/10.1186/s41021-022-00240-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966303/
https://www.ncbi.nlm.nih.gov/pubmed/35351212
http://dx.doi.org/10.1186/s41021-022-00240-7

Ejemplares similares