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Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina

A small proportion of infertile women experience repeated oocyte maturation abnormalities (OMAS). OMAS include degenerated and dysmorphic oocytes, empty follicle syndrome, oocyte maturation arrest (OMA), resistant ovary syndrome and maturation defects due to primary ovarian insufficiency. Genetic fa...

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Autores principales: Hatırnaz, Şafak, Saynur Hatırnaz, Ebru, Ellibeş Kaya, Aşkı, Hatırnaz, Kaan, Soyer Çalışkan, Canan, Sezer, Özlem, Dokuzeylül Güngor, Nur, Demirel, Cem, Baltacı, Volkan, Tan, Seang, Dahan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966321/
https://www.ncbi.nlm.nih.gov/pubmed/35343221
http://dx.doi.org/10.4274/tjod.galenos.2022.76329
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author Hatırnaz, Şafak
Saynur Hatırnaz, Ebru
Ellibeş Kaya, Aşkı
Hatırnaz, Kaan
Soyer Çalışkan, Canan
Sezer, Özlem
Dokuzeylül Güngor, Nur
Demirel, Cem
Baltacı, Volkan
Tan, Seang
Dahan, Michael
author_facet Hatırnaz, Şafak
Saynur Hatırnaz, Ebru
Ellibeş Kaya, Aşkı
Hatırnaz, Kaan
Soyer Çalışkan, Canan
Sezer, Özlem
Dokuzeylül Güngor, Nur
Demirel, Cem
Baltacı, Volkan
Tan, Seang
Dahan, Michael
author_sort Hatırnaz, Şafak
collection PubMed
description A small proportion of infertile women experience repeated oocyte maturation abnormalities (OMAS). OMAS include degenerated and dysmorphic oocytes, empty follicle syndrome, oocyte maturation arrest (OMA), resistant ovary syndrome and maturation defects due to primary ovarian insufficiency. Genetic factors play an important role in OMAS but still need specifications. This review documents the spectrum of OMAS and to evaluate the multiple subtypes classified as OMAS. In this review, readers will be able to understand the oocyte maturation mechanism, gene expression and their regulation that lead to different subtypes of OMAs, and it will discuss the animal and human studies related to OMAS and lastly the treatment options for OMAs. Literature searches using PubMed, MEDLINE, Embase, National Institute for Health and Care Excellence were performed to identify articles written in English focusing on Oocyte Maturation Abnormalities by looking for the following relevant keywords. A search was made with the specified keywords and included books and documents, clinical trials, animal studies, human studies, meta-analysis, randomized controlled trials, reviews, systematic reviews and options written in english. The search detected 3,953 sources published from 1961 to 2021. After title and abstract screening for study type, duplicates and relevancy, 2,914 studies were excluded. The remaining 1,039 records were assessed for eligibility by full-text reading and 886 records were then excluded. Two hundred and twenty seven full-text articles and 0 book chapters from the database were selected for inclusion. Overall, 227 articles, one unpublished and one abstract paper were included in this final review. In this review study, OMAS were classified and extensively evaluatedand possible treatment options under the light of current information, present literature and ongoing studies. Either genetic studies or in vitro maturation studies that will be handled in the future will lead more informations to be reached and may make it possible to obtain pregnancies.
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spelling pubmed-89663212022-04-08 Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina Hatırnaz, Şafak Saynur Hatırnaz, Ebru Ellibeş Kaya, Aşkı Hatırnaz, Kaan Soyer Çalışkan, Canan Sezer, Özlem Dokuzeylül Güngor, Nur Demirel, Cem Baltacı, Volkan Tan, Seang Dahan, Michael Turk J Obstet Gynecol Review A small proportion of infertile women experience repeated oocyte maturation abnormalities (OMAS). OMAS include degenerated and dysmorphic oocytes, empty follicle syndrome, oocyte maturation arrest (OMA), resistant ovary syndrome and maturation defects due to primary ovarian insufficiency. Genetic factors play an important role in OMAS but still need specifications. This review documents the spectrum of OMAS and to evaluate the multiple subtypes classified as OMAS. In this review, readers will be able to understand the oocyte maturation mechanism, gene expression and their regulation that lead to different subtypes of OMAs, and it will discuss the animal and human studies related to OMAS and lastly the treatment options for OMAs. Literature searches using PubMed, MEDLINE, Embase, National Institute for Health and Care Excellence were performed to identify articles written in English focusing on Oocyte Maturation Abnormalities by looking for the following relevant keywords. A search was made with the specified keywords and included books and documents, clinical trials, animal studies, human studies, meta-analysis, randomized controlled trials, reviews, systematic reviews and options written in english. The search detected 3,953 sources published from 1961 to 2021. After title and abstract screening for study type, duplicates and relevancy, 2,914 studies were excluded. The remaining 1,039 records were assessed for eligibility by full-text reading and 886 records were then excluded. Two hundred and twenty seven full-text articles and 0 book chapters from the database were selected for inclusion. Overall, 227 articles, one unpublished and one abstract paper were included in this final review. In this review study, OMAS were classified and extensively evaluatedand possible treatment options under the light of current information, present literature and ongoing studies. Either genetic studies or in vitro maturation studies that will be handled in the future will lead more informations to be reached and may make it possible to obtain pregnancies. Galenos Publishing 2022-03 2022-03-28 /pmc/articles/PMC8966321/ /pubmed/35343221 http://dx.doi.org/10.4274/tjod.galenos.2022.76329 Text en ©Copyright 2022 by Turkish Society of Obstetrics and Gynecology | Turkish Journal of Obstetrics and Gynecology published by Galenos Publishing House. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Hatırnaz, Şafak
Saynur Hatırnaz, Ebru
Ellibeş Kaya, Aşkı
Hatırnaz, Kaan
Soyer Çalışkan, Canan
Sezer, Özlem
Dokuzeylül Güngor, Nur
Demirel, Cem
Baltacı, Volkan
Tan, Seang
Dahan, Michael
Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina
title Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina
title_full Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina
title_fullStr Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina
title_full_unstemmed Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina
title_short Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina
title_sort oocyte maturation abnormalities - a systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966321/
https://www.ncbi.nlm.nih.gov/pubmed/35343221
http://dx.doi.org/10.4274/tjod.galenos.2022.76329
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