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Cholesterol sensor SCAP contributes to sorafenib resistance by regulating autophagy in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most malignant tumors and the fourth leading cause of cancer-related death worldwide. Sorafenib is currently acknowledged as a standard therapy for advanced HCC. However, acquired resistance substantially limits the clinical efficacy of sorafe...

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Detalles Bibliográficos
Autores principales:	Li, Danyang, Yao, Yingcheng, Rao, Yuhan, Huang, Xinyu, Wei, Li, You, Zhimei, Zheng, Guo, Hou, Xiaoli, Su, Yu, Varghese, Zac, Moorhead, John F., Chen, Yaxi, Ruan, Xiong Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966370/ https://www.ncbi.nlm.nih.gov/pubmed/35354475 http://dx.doi.org/10.1186/s13046-022-02306-4

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