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Propofol Protects Myocardium From Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through the AKT/p53 Signaling Pathway

The molecular mechanism underlying the protective role of propofol against myocardial ischemia/reperfusion (I/R) injury remains poorly understood. Previous studies have shown that ferroptosis is an imperative pathological process in myocardial I/R injury. We hypothesized that propofol prevents myoca...

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Detalles Bibliográficos
Autores principales: Li, Shengqiang, Lei, Zhen, Yang, Xiaomei, Zhao, Meng, Hou, Yonghao, Wang, Di, Tang, Shuhai, Li, Jingxin, Yu, Jingui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966655/
https://www.ncbi.nlm.nih.gov/pubmed/35370724
http://dx.doi.org/10.3389/fphar.2022.841410