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Mitochondrial DNA Release Contributes to Intestinal Ischemia/Reperfusion Injury

Mitochondria release many damage-associated molecular patterns (DAMPs) when cells are damaged or stressed, with mitochondrial DNA (mtDNA) being. MtDNA activates innate immune responses and induces inflammation through the TLR-9, NLRP3 inflammasome, and cGAS-STING signaling pathways. Released inflamm...

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Detalles Bibliográficos
Autores principales:	Liao, Shishi, Luo, Jie, Kadier, Tulanisa, Ding, Ke, Chen, Rong, Meng, Qingtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966724/ https://www.ncbi.nlm.nih.gov/pubmed/35370747 http://dx.doi.org/10.3389/fphar.2022.854994

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