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Antiviral cyclic peptides targeting the main protease of SARS-CoV-2

Antivirals that specifically target SARS-CoV-2 are needed to control the COVID-19 pandemic. The main protease (M(pro)) is essential for SARS-CoV-2 replication and is an attractive target for antiviral development. Here we report the use of the Random nonstandard Peptide Integrated Discovery (RaPID)...

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Detalles Bibliográficos
Autores principales:	Johansen-Leete, Jason, Ullrich, Sven, Fry, Sarah E., Frkic, Rebecca, Bedding, Max J., Aggarwal, Anupriya, Ashhurst, Anneliese S., Ekanayake, Kasuni B., Mahawaththa, Mithun C., Sasi, Vishnu M., Luedtke, Stephanie, Ford, Daniel J., O'Donoghue, Anthony J., Passioura, Toby, Larance, Mark, Otting, Gottfried, Turville, Stuart, Jackson, Colin J., Nitsche, Christoph, Payne, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966731/ https://www.ncbi.nlm.nih.gov/pubmed/35432913 http://dx.doi.org/10.1039/d1sc06750h

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