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Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design

Photoaffinity labeling (PAL) is a powerful tool for the identification of non-covalent small molecule–protein interactions that are critical to drug discovery and medicinal chemistry, but this approach is limited to only a small subset of robust photocrosslinkers. The identification of new photoreac...

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Detalles Bibliográficos
Autores principales: Page, Annika C. S., Scholz, Spencer O., Keenan, Katherine N., Spradlin, Jessica N., Belcher, Bridget P., Brittain, Scott M., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Nomura, Daniel K., Toste, F. Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966736/
https://www.ncbi.nlm.nih.gov/pubmed/35432890
http://dx.doi.org/10.1039/d2sc00426g