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Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design
Photoaffinity labeling (PAL) is a powerful tool for the identification of non-covalent small molecule–protein interactions that are critical to drug discovery and medicinal chemistry, but this approach is limited to only a small subset of robust photocrosslinkers. The identification of new photoreac...
Autores principales: | Page, Annika C. S., Scholz, Spencer O., Keenan, Katherine N., Spradlin, Jessica N., Belcher, Bridget P., Brittain, Scott M., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Nomura, Daniel K., Toste, F. Dean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966736/ https://www.ncbi.nlm.nih.gov/pubmed/35432890 http://dx.doi.org/10.1039/d2sc00426g |
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