Cargando…
Poxvirus MVA Expressing SARS-CoV-2 S Protein Induces Robust Immunity and Protects Rhesus Macaques From SARS-CoV-2
Novel safe, immunogenic, and effective vaccines are needed to control the COVID-19 pandemic, caused by SARS-CoV-2. Here, we describe the safety, robust immunogenicity, and potent efficacy elicited in rhesus macaques by a modified vaccinia virus Ankara (MVA) vector expressing a full-length SARS-CoV-2...
Autores principales: | Mooij, Petra, García-Arriaza, Juan, Pérez, Patricia, Lázaro-Frías, Adrian, Verstrepen, Babs E., Böszörményi, Kinga P., Mortier, Daniella, Fagrouch, Zahra, Kiemenyi-Kayere, Gwendoline, Niphuis, Henk, Acar, Roja Fidel, Meijer, Lisette, Stammes, Marieke A., Kondova, Ivanela, Verschoor, Ernst J., GeurtsvanKessel, Corine H., de Bruin, Erwin, Sikkema, Reina S., Luczkowiak, Joanna, Delgado, Rafael, Montenegro, Dolores, Puentes, Eugenia, Rodríguez, Esteban, Bogers, Willy M. J. M., Koopman, Gerrit, Esteban, Mariano |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966779/ https://www.ncbi.nlm.nih.gov/pubmed/35371043 http://dx.doi.org/10.3389/fimmu.2022.845887 |
Ejemplares similares
-
A low dose of RBD and TLR7/8 agonist displayed on influenza virosome particles protects rhesus macaque against SARS-CoV-2 challenge
por: Koopman, Gerrit, et al.
Publicado: (2023) -
The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues
por: Böszörményi, Kinga P., et al.
Publicado: (2021) -
Novel application of [(18)F]DPA714 for visualizing the pulmonary inflammation process of SARS-CoV-2-infection in rhesus monkeys (Macaca mulatta)
por: Meijer, Lisette, et al.
Publicado: (2022) -
A Bacterially-Expressed Recombinant Envelope Protein from Usutu Virus Induces Neutralizing Antibodies in Rabbits
por: Böszörményi, Kinga, et al.
Publicado: (2021) -
Bronchoalveolar lavage affects thorax computed tomography of healthy and SARS-CoV-2 infected rhesus macaques (Macaca mulatta)
por: Maaskant, Annemiek, et al.
Publicado: (2021)