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Injectable decellularized nucleus pulposus tissue exhibits neuroinhibitory properties

BACKGROUND: Chronic low back pain (LBP) is a leading cause of disability, but treatments for LBP are limited. Degeneration of the intervertebral disc due to loss of neuroinhibitory sulfated glycosaminoglycans (sGAGs) allows nerves from dorsal root ganglia to grow into the core of the disc. Treatment...

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Detalles Bibliográficos
Autores principales: Piening, Logan M., Lillyman, David J., Lee, Fei San, Lozano, Alvaro Moreno, Miles, Jeremy R., Wachs, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966883/
https://www.ncbi.nlm.nih.gov/pubmed/35386760
http://dx.doi.org/10.1002/jsp2.1187