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Dissecting the cellular components of ex vivo γδ T cell expansions to optimize selection of potent cell therapy donors for neuroblastoma immunotherapy trials

γδ T lymphocytes represent an emerging class of cellular immunotherapy with preclinical promise to treat cancer, notably neuroblastoma. The innate-like immune cell subset demonstrates inherent cytoxicity toward tumor cells independent of MHC recognition, enabling allogeneic administration of healthy...

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Detalles Bibliográficos
Autores principales:	Jonus, Hunter C., Burnham, Rebecca E., Ho, Andrew, Pilgrim, Adeiye A., Shim, Jenny, Doering, Christopher B., Spencer, H. Trent, Goldsmith, Kelly C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966991/ https://www.ncbi.nlm.nih.gov/pubmed/35371623 http://dx.doi.org/10.1080/2162402X.2022.2057012

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