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Structure-based dual affinity optimization of a SARS-CoV-1/2 cross-reactive single-domain antibody

The SARS coronavirus 2 (SARS-CoV-2) spike (S) protein binding to the human ACE2 receptor is the molecular event that initiates viral entry into host cells and leads to infection and virus replication. There is a need for agents blocking viral entry into host cells that are cross-reactive with emergi...

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Detalles Bibliográficos
Autores principales:	Sulea, Traian, Baardsnes, Jason, Stuible, Matthew, Rohani, Nazanin, Tran, Anh, Parat, Marie, Cepero Donates, Yuneivy, Duchesne, Mélanie, Plante, Pierre, Kour, Guneet, Durocher, Yves
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967028/ https://www.ncbi.nlm.nih.gov/pubmed/35353868 http://dx.doi.org/10.1371/journal.pone.0266250

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