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HIV-1 infections with multiple founders associate with the development of neutralization breadth

Eliciting broadly neutralizing antibodies (bnAbs) is a cornerstone of HIV-1 vaccine strategies. Comparing HIV-1 envelope (env) sequences from the first weeks of infection to the breadth of antibody responses observed several years after infection can help define viral features critical to vaccine de...

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Detalles Bibliográficos
Autores principales: Lewitus, Eric, Townsley, Samantha M., Li, Yifan, Donofrio, Gina C., Dearlove, Bethany L., Bai, Hongjun, Sanders-Buell, Eric, O’Sullivan, Anne Marie, Bose, Meera, Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Sawe, Fredrick K., Eller, Leigh Anne, Michael, Nelson L., Polonis, Victoria R., Ake, Julie A., Vasan, Sandhya, Robb, Merlin L., Tovanabutra, Sodsai, Krebs, Shelly J., Rolland, Morgane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967031/
https://www.ncbi.nlm.nih.gov/pubmed/35303045
http://dx.doi.org/10.1371/journal.ppat.1010369