Cargando…

Mechanism of Borrelia immune evasion by FhbA-related proteins

Immune evasion facilitates survival of Borrelia, leading to infections like relapsing fever and Lyme disease. Important mechanism for complement evasion is acquisition of the main host complement inhibitor, factor H (FH). By determining the 2.2 Å crystal structure of Factor H binding protein A (FhbA...

Descripción completa

Detalles Bibliográficos
Autores principales: Kogan, Konstantin, Haapasalo, Karita, Kotila, Tommi, Moore, Robin, Lappalainen, Pekka, Goldman, Adrian, Meri, Taru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967061/
https://www.ncbi.nlm.nih.gov/pubmed/35303742
http://dx.doi.org/10.1371/journal.ppat.1010338