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Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors

Introduction: The relationship between cancers and thromboembolic events is well established. In our study, we aim to determine the burden of thromboembolic events in patients with solid tumors and identify the risk factors related to their development. Materials & Methods: Data on patients with...

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Autores principales: Bazarbashi, Shouki, Alkhaldi, Turkiah, Aseafan, Mohamed, Melaibari, Maryam, Almuhisen, Sara, Alharbi, Samar, Alghabban, Abdulrahman, Aljumaa, Jihad, Eldali, Abdelmoneim, Maraiki, Fatma, Owaidah, Tarek, Alzahrani, Hazzaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967125/
https://www.ncbi.nlm.nih.gov/pubmed/35386484
http://dx.doi.org/10.7759/cureus.23624
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author Bazarbashi, Shouki
Alkhaldi, Turkiah
Aseafan, Mohamed
Melaibari, Maryam
Almuhisen, Sara
Alharbi, Samar
Alghabban, Abdulrahman
Aljumaa, Jihad
Eldali, Abdelmoneim
Maraiki, Fatma
Owaidah, Tarek
Alzahrani, Hazzaa
author_facet Bazarbashi, Shouki
Alkhaldi, Turkiah
Aseafan, Mohamed
Melaibari, Maryam
Almuhisen, Sara
Alharbi, Samar
Alghabban, Abdulrahman
Aljumaa, Jihad
Eldali, Abdelmoneim
Maraiki, Fatma
Owaidah, Tarek
Alzahrani, Hazzaa
author_sort Bazarbashi, Shouki
collection PubMed
description Introduction: The relationship between cancers and thromboembolic events is well established. In our study, we aim to determine the burden of thromboembolic events in patients with solid tumors and identify the risk factors related to their development. Materials & Methods: Data on patients with solid tumors and thromboembolism between January 2013 and September 2014 were collected and analyzed. Results: During the study period 174 patients were identified. Of which, 172 (98.9%) had venous thrombus embolism, 137 (79%) were diagnosed with deep vein thromboses, 67 (38.5%) with pulmonary embolism, 84 (48.3%) were symptomatic and 90 (51.7) were incidental at diagnosis. The most common patients and disease characteristics were female sex, high body mass index (BMI), metastatic stage, colorectal and breast primaries, and anti-neoplastic therapy. Conclusion: Our study confirmed the high burden of thromboembolic events in cancer patients and the relevant factors associated with its development.
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spelling pubmed-89671252022-04-05 Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors Bazarbashi, Shouki Alkhaldi, Turkiah Aseafan, Mohamed Melaibari, Maryam Almuhisen, Sara Alharbi, Samar Alghabban, Abdulrahman Aljumaa, Jihad Eldali, Abdelmoneim Maraiki, Fatma Owaidah, Tarek Alzahrani, Hazzaa Cureus Oncology Introduction: The relationship between cancers and thromboembolic events is well established. In our study, we aim to determine the burden of thromboembolic events in patients with solid tumors and identify the risk factors related to their development. Materials & Methods: Data on patients with solid tumors and thromboembolism between January 2013 and September 2014 were collected and analyzed. Results: During the study period 174 patients were identified. Of which, 172 (98.9%) had venous thrombus embolism, 137 (79%) were diagnosed with deep vein thromboses, 67 (38.5%) with pulmonary embolism, 84 (48.3%) were symptomatic and 90 (51.7) were incidental at diagnosis. The most common patients and disease characteristics were female sex, high body mass index (BMI), metastatic stage, colorectal and breast primaries, and anti-neoplastic therapy. Conclusion: Our study confirmed the high burden of thromboembolic events in cancer patients and the relevant factors associated with its development. Cureus 2022-03-29 /pmc/articles/PMC8967125/ /pubmed/35386484 http://dx.doi.org/10.7759/cureus.23624 Text en Copyright © 2022, Bazarbashi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Bazarbashi, Shouki
Alkhaldi, Turkiah
Aseafan, Mohamed
Melaibari, Maryam
Almuhisen, Sara
Alharbi, Samar
Alghabban, Abdulrahman
Aljumaa, Jihad
Eldali, Abdelmoneim
Maraiki, Fatma
Owaidah, Tarek
Alzahrani, Hazzaa
Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors
title Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors
title_full Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors
title_fullStr Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors
title_full_unstemmed Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors
title_short Thromboembolic Events Burden in Patients With Solid Tumors and Their Predisposing Factors
title_sort thromboembolic events burden in patients with solid tumors and their predisposing factors
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967125/
https://www.ncbi.nlm.nih.gov/pubmed/35386484
http://dx.doi.org/10.7759/cureus.23624
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