Baicalein Ameliorates Myocardial Ischemia Through Reduction of Oxidative Stress, Inflammation and Apoptosis via TLR4/MyD88/MAPK(S)/NF-κB Pathway and Regulation of Ca(2+) Homeostasis by L-type Ca(2+) Channels

Background: Baicalein (Bai) is the principal ingredient of Scutellaria baicalensis Georgi. Reports concerning the therapeutic advantages in treating cardiovascular diseases have been published. However, its protective mechanism towards myocardial ischemia (MI) is undefined. Objective: The aim of thi...

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Detalles Bibliográficos
Autores principales: Li, Jinghan, Yang, Yakun, Wang, Hua, Ma, Donglai, Wang, Hongfang, Chu, Li, Zhang, Yuanyuan, Gao, Yonggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967179/
https://www.ncbi.nlm.nih.gov/pubmed/35370644
http://dx.doi.org/10.3389/fphar.2022.842723

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