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High-throughput identification of autoantibodies that target the human exoproteome

Autoantibodies that recognize extracellular proteins (the exoproteome) exert potent biological effects but are challenging to detect. Here, we developed rapid extracellular antigen profiling (REAP), a high-throughput technique for the comprehensive discovery of exoproteome-targeting autoantibodies....

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Detalles Bibliográficos
Autores principales: Wang, Eric Y., Dai, Yile, Rosen, Connor E., Schmitt, Monica M., Dong, Mei X., Ferré, Elise M.N., Liu, Feimei, Yang, Yi, González-Hernández, Jaime A., Meffre, Eric, Hinchcliff, Monique, Koumpouras, Fotios, Lionakis, Michail S., Ring, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967185/
https://www.ncbi.nlm.nih.gov/pubmed/35360706
http://dx.doi.org/10.1016/j.crmeth.2022.100172

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