The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation

The cohesin complex is central to chromatin looping, but mechanisms by which these long-range chromatin interactions are formed and persist remain unclear. We demonstrate that interactions between a transcription factor (TF) and the cohesin loader NIPBL regulate enhancer-dependent gene activity. Usi...

Descripción completa

Detalles Bibliográficos
Autores principales: Rinaldi, Lorenzo, Fettweis, Gregory, Kim, Sohyoung, Garcia, David A., Fujiwara, Saori, Johnson, Thomas A., Tettey, Theophilus T., Ozbun, Laurent, Pegoraro, Gianluca, Puglia, Michele, Blagoev, Blagoy, Upadhyaya, Arpita, Stavreva, Diana A., Hager, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967222/
https://www.ncbi.nlm.nih.gov/pubmed/35353576
http://dx.doi.org/10.1126/sciadv.abj8360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967222/
https://www.ncbi.nlm.nih.gov/pubmed/35353576
http://dx.doi.org/10.1126/sciadv.abj8360

Ejemplares similares