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Synthetic Red Blood Cell-Specific Glycolytic Intermediate 2,3-Diphosphoglycerate (2,3-DPG) Inhibits Plasmodium falciparum Development In Vitro

Mechanisms of malaria parasite interaction with its host red blood cell may provide potential targets for new antimalarial approaches. Pyruvate kinase deficiency has been associated with resistance to malaria in both experimental models and population studies. Two of the major pyruvate kinase defici...

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Detalles Bibliográficos
Autores principales: Morais, Inês, Medeiros, Márcia M., Carvalho, Maria, Morello, Judit, Teixeira, Sara M., Maciel, Suelma, Nhantumbo, Janice, Balau, Ana, Rosa, Margarida T. G., Nogueira, Fátima, Rodrigues, João Alexandre, Carvalho, Filomena A., Antunes, Alexandra M. M., Arez, Ana Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967366/
https://www.ncbi.nlm.nih.gov/pubmed/35372095
http://dx.doi.org/10.3389/fcimb.2022.840968