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Synthetic Red Blood Cell-Specific Glycolytic Intermediate 2,3-Diphosphoglycerate (2,3-DPG) Inhibits Plasmodium falciparum Development In Vitro
Mechanisms of malaria parasite interaction with its host red blood cell may provide potential targets for new antimalarial approaches. Pyruvate kinase deficiency has been associated with resistance to malaria in both experimental models and population studies. Two of the major pyruvate kinase defici...
Autores principales: | Morais, Inês, Medeiros, Márcia M., Carvalho, Maria, Morello, Judit, Teixeira, Sara M., Maciel, Suelma, Nhantumbo, Janice, Balau, Ana, Rosa, Margarida T. G., Nogueira, Fátima, Rodrigues, João Alexandre, Carvalho, Filomena A., Antunes, Alexandra M. M., Arez, Ana Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967366/ https://www.ncbi.nlm.nih.gov/pubmed/35372095 http://dx.doi.org/10.3389/fcimb.2022.840968 |
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