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Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics
With the development of antibacterial, synergistic, and drug resistance research, the requirements for the specificity of antibiotics are getting higher and higher. In the research based on the specificity of antibiotics, this article uses intelligent medical image processing methods to study the sp...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967524/ https://www.ncbi.nlm.nih.gov/pubmed/35371276 http://dx.doi.org/10.1155/2022/6103649 |
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author | Xing, Yanxia An, Xiaowen Wang, Boyang Chang, Guifang Zhu, He Yu, Yang |
author_facet | Xing, Yanxia An, Xiaowen Wang, Boyang Chang, Guifang Zhu, He Yu, Yang |
author_sort | Xing, Yanxia |
collection | PubMed |
description | With the development of antibacterial, synergistic, and drug resistance research, the requirements for the specificity of antibiotics are getting higher and higher. In the research based on the specificity of antibiotics, this article uses intelligent medical image processing methods to study the specificity of the antibacterial efficiency of nanocopper oxide and the inhibition of drug resistance. Copper oxide nanorods have the properties of surface effect, quantum size effect, volume effect, and macroscopic quantum tunneling effect. Compared with ordinary copper oxide, the nanoscale gives them special properties of electricity, optics, and catalysis. In this article, in the research based on the specificity of antibiotics, the specificity of antimicrobial efficiency and drug resistance inhibition of nanocopper oxide are studied by using smart medical information processing methods. Drug sensitivity paper tablet method is a drug sensitivity experiment to determine drug sensitivity to make accurate and effective use of drugs for treatment. Colony growth method is used to take the equivalent volume of fermentation liquid at different times to determine the content of bacteria. In this article, Staphylococcus aureus is cultivated by the drug-sensitive disk method and the colony growth method. Then, according to this type of antibiotic and bacterial group combination, Staphylococcus aureus is divided into a penicillin group, nanocopper oxide group, and cephalosporin group. 0.5 g of the corresponding antibiotic was added to each group. TMP (trimethoprim) acts as a synergist, and the ratio of TMP to antibiotic is 1 : 5. Finally, we compared the inhibitory concentration indexes of the above three groups and inferred the synergistic effect of antibiotics and the inhibitory effect of drug resistance through the specificity of the antibiotics that the antibacterial activity was further studied. The results showed that the antibacterial effect of TMP combined with nano-CuO was 38% higher than that of the penicillin group and 41% higher than that of the cephalosporin group. In addition, the combined effect of TMP and antibiotics is greater than the combined effect of TMP and antibiotics alone. From the observation of smart medical system processing, it is speculated that the reason may be that they provide each other with a suitable environment. Because of this combined effect between the TMP and the antibiotic, it can influence each other. From the results, the combined effect is 48% higher than the combined effect. Therefore, according to the results of medical imaging, the combination of antibiotics and antibacterial synergists can improve specificity and antibacterial rate. |
format | Online Article Text |
id | pubmed-8967524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-89675242022-03-31 Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics Xing, Yanxia An, Xiaowen Wang, Boyang Chang, Guifang Zhu, He Yu, Yang Comput Math Methods Med Research Article With the development of antibacterial, synergistic, and drug resistance research, the requirements for the specificity of antibiotics are getting higher and higher. In the research based on the specificity of antibiotics, this article uses intelligent medical image processing methods to study the specificity of the antibacterial efficiency of nanocopper oxide and the inhibition of drug resistance. Copper oxide nanorods have the properties of surface effect, quantum size effect, volume effect, and macroscopic quantum tunneling effect. Compared with ordinary copper oxide, the nanoscale gives them special properties of electricity, optics, and catalysis. In this article, in the research based on the specificity of antibiotics, the specificity of antimicrobial efficiency and drug resistance inhibition of nanocopper oxide are studied by using smart medical information processing methods. Drug sensitivity paper tablet method is a drug sensitivity experiment to determine drug sensitivity to make accurate and effective use of drugs for treatment. Colony growth method is used to take the equivalent volume of fermentation liquid at different times to determine the content of bacteria. In this article, Staphylococcus aureus is cultivated by the drug-sensitive disk method and the colony growth method. Then, according to this type of antibiotic and bacterial group combination, Staphylococcus aureus is divided into a penicillin group, nanocopper oxide group, and cephalosporin group. 0.5 g of the corresponding antibiotic was added to each group. TMP (trimethoprim) acts as a synergist, and the ratio of TMP to antibiotic is 1 : 5. Finally, we compared the inhibitory concentration indexes of the above three groups and inferred the synergistic effect of antibiotics and the inhibitory effect of drug resistance through the specificity of the antibiotics that the antibacterial activity was further studied. The results showed that the antibacterial effect of TMP combined with nano-CuO was 38% higher than that of the penicillin group and 41% higher than that of the cephalosporin group. In addition, the combined effect of TMP and antibiotics is greater than the combined effect of TMP and antibiotics alone. From the observation of smart medical system processing, it is speculated that the reason may be that they provide each other with a suitable environment. Because of this combined effect between the TMP and the antibiotic, it can influence each other. From the results, the combined effect is 48% higher than the combined effect. Therefore, according to the results of medical imaging, the combination of antibiotics and antibacterial synergists can improve specificity and antibacterial rate. Hindawi 2022-03-23 /pmc/articles/PMC8967524/ /pubmed/35371276 http://dx.doi.org/10.1155/2022/6103649 Text en Copyright © 2022 Yanxia Xing et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Xing, Yanxia An, Xiaowen Wang, Boyang Chang, Guifang Zhu, He Yu, Yang Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics |
title | Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics |
title_full | Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics |
title_fullStr | Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics |
title_full_unstemmed | Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics |
title_short | Mechanism of Antibacterial Enhancement and Drug Resistance Based on Smart Medical Imaging on Antibiotics |
title_sort | mechanism of antibacterial enhancement and drug resistance based on smart medical imaging on antibiotics |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967524/ https://www.ncbi.nlm.nih.gov/pubmed/35371276 http://dx.doi.org/10.1155/2022/6103649 |
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