Cargando…

Identification of Potential Poly (ADP-Ribose) Polymerase-1 Inhibitors Derived from Rauwolfia serpentina: Possible Implication in Cancer Therapy

Poly (ADP-ribose) polymerase-1 (PARP-1) has been recognized as a prospective target for the development of novel cancer therapeutics. Several PARP-1 inhibitors are currently being considered for anticancer drug development and clinical investigation. Lately, natural compounds seem to be excellent al...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abuzenadah, Adel M., Al-Sayes, Fatin, Mahafujul Alam, Syed Sahajada, Hoque, Mehboob, Karim, Sajjad, Hussain, Ibtessam M. R., Tabrez, Shams
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967534/ https://www.ncbi.nlm.nih.gov/pubmed/35368755 http://dx.doi.org/10.1155/2022/3787162

Ejemplares similares

Elucidating Antiangiogenic Potential of Rauwolfia serpentina: VEGFR-2 Targeting-Based Molecular Docking Study
por: Abuzenadah, Adel M., et al.
Publicado: (2022)

Retracted: Identification of Potential Poly (ADP-Ribose) Polymerase-1 Inhibitors Derived from Rauwolfia serpentina: Possible Implication in Cancer Therapy
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Rauwolfia Serpentina in Essential Hypertension
por: Chakravarty, N. K., et al.
Publicado: (1951)

Curcumin and Plumbagin Synergistically Target the PI3K/Akt/mTOR Pathway: A Prospective Role in Cancer Treatment
por: Ahmad, Iftikhar, et al.
Publicado: (2023)

Preliminary Observations on the Use of Rauwolfia Serpentina Benth. In the Treatment of Mental Disorders
por: Gupta, J. C., et al.
Publicado: (1943)

Antihypertensive and Antihyperlipidemic Activity of Aqueous Methanolic Extract of Rauwolfia Serpentina in Albino Rats
por: Shah, Syed Muhammad Ali, et al.
Publicado: (2020)

Analyzing the interaction of human ACE2 and RBD of spike protein of SARS-CoV-2 in perspective of Omicron variant
por: Samanta, Arijit, et al.
Publicado: (2022)

Evaluating the transmission feasibility of SARS-CoV-2 Omicron (B.1.1.529) variant to 143 mammalian hosts: insights from S protein RBD and host ACE2 interaction studies
por: Samanta, Arijit, et al.
Publicado: (2023)

RNA regulation by Poly(ADP-ribose) polymerases
por: Bock, Florian J., et al.
Publicado: (2015)

Mitotic functions of poly(ADP-ribose) polymerases
por: Slade, Dea
Publicado: (2019)

The Antiviral Activities of Poly-ADP-Ribose Polymerases
por: Malgras, Mathilde, et al.
Publicado: (2021)

Elicitation Based Enhancement of Secondary Metabolites in Rauwolfia serpentina and Solanum khasianum Hairy Root Cultures
por: Srivastava, Mrinalini, et al.
Publicado: (2016)

Bioprospecting of the novel isolate Microbacterium proteolyticum LA2(R) from the rhizosphere of Rauwolfia serpentina
por: Bano, Naushin, et al.
Publicado: (2022)

A Priliminary Note on the Pharmacological Study on Reserpine a New Alkaloid Isolated from Rauwolfia Serpentina
por: Chowhan, J. S., et al.
Publicado: (1954)

Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma
por: Vormoor, Britta, et al.
Publicado: (2014)

Role of poly(ADP-ribose) polymerases in male reproduction
por: Celik-Ozenci, Ciler, et al.
Publicado: (2013)

Inhibition of Poly ADP-Ribose Glycohydrolase Sensitizes Ovarian Cancer Cells to Poly ADP-Ribose Polymerase Inhibitors and Platinum Agents
por: Matanes, Emad, et al.
Publicado: (2021)

Stability of centrosome numbers in poly(ADP-ribose) polymerase-1- and poly(ADP-ribose) glycohydrolase-deficient mouse ES cells
por: Ogino, Hideki, et al.
Publicado: (2004)

Pancreatic β-Cell Death, Regeneration and Insulin Secretion: Roles of Poly(ADP-Ribose) Polymerase and Cyclic ADP-Ribose
por: Takasawa, Shin, et al.
Publicado: (2002)

Loss of amplified genes by poly(ADP-ribose) polymerase inhibitors.
por: Nagao, M, et al.
Publicado: (1991)

Targeting poly(ADP-ribose) polymerase activity for cancer therapy
por: Mégnin-Chanet, Frédérique, et al.
Publicado: (2010)

Lipoxygenases and Poly(ADP-Ribose) Polymerase in Amyloid Beta Cytotoxicity
por: Strosznajder, Joanna B., et al.
Publicado: (2011)

Analysis of Poly(ADP-Ribose) Polymerases in Arabidopsis Telomere Biology
por: Boltz, Kara A., et al.
Publicado: (2014)

The Role of Poly(ADP-ribose) Polymerase-1 in Rheumatoid Arthritis
por: García, Samuel, et al.
Publicado: (2015)

Poly (ADP-ribose) polymerase inhibitors in the management of ovarian cancer
por: Markman, Maurie
Publicado: (2018)

Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy
por: Jannetti, Stephen A., et al.
Publicado: (2020)

Poly(ADP-Ribose) Polymerase-3 Regulates Regeneration in Planarians
por: Barghouth, Paul G., et al.
Publicado: (2020)

New Facets in the Regulation of Gene Expression by ADP-Ribosylation and Poly(ADP-ribose) Polymerases
por: Ryu, Keun Woo, et al.
Publicado: (2015)

Methanolic Root Extract of Rauwolfia serpentina Benth Improves the Glycemic, Antiatherogenic, and Cardioprotective Indices in Alloxan-Induced Diabetic Mice
por: Azmi, Muhammad Bilal, et al.
Publicado: (2012)

In silico investigation on alkaloids of Rauwolfia serpentina as potential inhibitors of 3-hydroxy-3-methyl-glutaryl-CoA reductase
por: Azmi, Muhammad Bilal, et al.
Publicado: (2021)

The role of poly (ADP-ribose) polymerase in ventilator-induced lung injury
por: Vaneker, Michiel, et al.
Publicado: (2008)

Poly(ADP-ribose) polymerase inhibitor development: are we in the right direction?
por: Plummer, R
Publicado: (2011)

Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes
por: Citarelli, Matteo, et al.
Publicado: (2010)

Poly (ADP-Ribose) Polymerase Mediates Diabetes-Induced Retinal Neuropathy
por: Mohammad, Ghulam, et al.
Publicado: (2013)

Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and Tumorogenesis
por: Jiang, Bo-Hua, et al.
Publicado: (2015)

Multiple facets of poly(ADP-ribose) polymerase-1 in neurological diseases
por: Sriram, Chandra Shaker, et al.
Publicado: (2015)

The promising role of poly(ADP-ribose) polymerase inhibitors in prostate cancer
por: Aragon-Ching, Jeanny B
Publicado: (2016)

Update on Poly-ADP-ribose polymerase inhibition for ovarian cancer treatment
por: Papa, Anselmo, et al.
Publicado: (2016)

Current status of poly(ADP-ribose) polymerase inhibitors and future directions
por: Ohmoto, Akihiro, et al.
Publicado: (2017)

Poly(ADP-Ribose) Polymerases in Plants and Their Human Counterparts: Parallels and Peculiarities
por: Rissel, Dagmar, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dg6vh75emb6kbjt9pj3eks9t54