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MnTE-2-PyP protects fibroblast mitochondria from hyperglycemia and radiation exposure

Radiation is a common anticancer therapy for prostate cancer, which transforms tumor-associated normal fibroblasts to myofibroblasts, resulting in fibrosis. Oxidative stress caused by radiation-mediated mitochondrial damage is one of the major contributors to fibrosis. As diabetics are oxidatively s...

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Detalles Bibliográficos
Autores principales: Chatterjee, Arpita, Sakallioglu, Isin T., Murthy, Divya, Kosmacek, Elizabeth A., Singh, Pankaj K., McDonald, J. Tyson, Powers, Robert, Oberley-Deegan, Rebecca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967707/
https://www.ncbi.nlm.nih.gov/pubmed/35358851
http://dx.doi.org/10.1016/j.redox.2022.102301