Inhibition of calcium-triggered secretion by hydrocarbon-stapled peptides

Membrane fusion triggered by Ca(2+) is orchestrated by a conserved set of proteins to mediate synaptic neurotransmitter release, mucin secretion and other regulated exocytic processes(1–4). For neurotransmitter release, the Ca(2+) sensitivity is introduced by interactions between the Ca(2+) sensor s...

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Detalles Bibliográficos
Autores principales: Lai, Ying, Fois, Giorgio, Flores, Jose R., Tuvim, Michael J., Zhou, Qiangjun, Yang, Kailu, Leitz, Jeremy, Peters, John, Zhang, Yunxiang, Pfuetzner, Richard A., Esquivies, Luis, Jones, Philip, Frick, Manfred, Dickey, Burton F., Brunger, Axel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967716/
https://www.ncbi.nlm.nih.gov/pubmed/35322233
http://dx.doi.org/10.1038/s41586-022-04543-1

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