Myelodysplastic/ Myeloproliferative Neoplasms-Unclassifiable (MDS/MPN-U) with Isolated Isochromosome 17q Represents a Distinct Clinico-Biologic Subset: A Multi-institutional Collaborative Study from the Bone Marrow Pathology Group

Classification of myeloid neoplasms with isolated i(17q) [17p deletion with inherent monoallelic TP53 loss plus 17q duplication] is controversial. Most cases fall within the WHO unclassifiable myelodysplastic/myeloproliferative neoplasms (MDS/MPN-U) category. The uniformly dismal outcomes warrant be...

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Detalles Bibliográficos
Autores principales: Kanagal-Shamanna, Rashmi, Orazi, Attilio, Hasserjian, Robert P., Arber, Daniel A., Reichard, Kaaren, Hsi, Eric D., Bagg, Adam, Rogers, Heesun Joyce, Geyer, Julia, Darbaniyan, Faezeh, Do, Kim-Anh, Devins, Kyle M., Pozdnyakova, Olga, George, Tracy I., Cin, Paola Dal, Greipp, Patricia T., Routbort, Mark J., Patel, Keyur, Garcia-Manero, Guillermo, Verstovsek, Srdan, Medeiros, L. Jeffrey, Wang, Sa A., Bueso-Ramos, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967812/
https://www.ncbi.nlm.nih.gov/pubmed/34775472
http://dx.doi.org/10.1038/s41379-021-00961-0

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