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Surgical outcomes of acute type A aortic dissection in dialysis patients: lessons learned from a single-center’s experience

There is a paucity of data describing the safety and efficacy of acute type A aortic dissection (ATAAD) repair surgeries in dialysis patients. Our study aimed to investigated the influence of dialysis on early and late outcomes in end-stage renal disease (ESRD) patients who received repair surgery f...

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Autores principales: Wang, Zhigang, Ge, Pingping, Lu, Lichong, Ge, Min, Chen, Cheng, Zhang, Lifang, Wang, Dongjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967816/
https://www.ncbi.nlm.nih.gov/pubmed/35354894
http://dx.doi.org/10.1038/s41598-022-09448-7
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author Wang, Zhigang
Ge, Pingping
Lu, Lichong
Ge, Min
Chen, Cheng
Zhang, Lifang
Wang, Dongjin
author_facet Wang, Zhigang
Ge, Pingping
Lu, Lichong
Ge, Min
Chen, Cheng
Zhang, Lifang
Wang, Dongjin
author_sort Wang, Zhigang
collection PubMed
description There is a paucity of data describing the safety and efficacy of acute type A aortic dissection (ATAAD) repair surgeries in dialysis patients. Our study aimed to investigated the influence of dialysis on early and late outcomes in end-stage renal disease (ESRD) patients who received repair surgery for ATAAD. A total of 882 ATAAD patients who received emergency aortic dissection repair at our center from January 2015 to December 2019 were retrospectively screened in this study and divided into the dialysis group (n = 16) and the non-dialysis group (n = 866), depending on whether they required dialysis for preoperative ESRD. No significant difference of age, preoperative hemodynamics, organ ischemia conditions, operative variables as well as the 30-Day mortality and in-hospital complications was discovered between two groups. However, the survival rates and the proportion of late aortic event (sudden death and reoperation) free population at 1 and 3 years after surgery were significantly decreased in dialysis patients compared to non-dialysis patients. Our study indicated that the short-term surgical outcomes of ATAAD in dialysis patients were comparable to non-dialysis patient. However, the dialysis patients were associated with a worse long-term prognosis.
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spelling pubmed-89678162022-04-01 Surgical outcomes of acute type A aortic dissection in dialysis patients: lessons learned from a single-center’s experience Wang, Zhigang Ge, Pingping Lu, Lichong Ge, Min Chen, Cheng Zhang, Lifang Wang, Dongjin Sci Rep Article There is a paucity of data describing the safety and efficacy of acute type A aortic dissection (ATAAD) repair surgeries in dialysis patients. Our study aimed to investigated the influence of dialysis on early and late outcomes in end-stage renal disease (ESRD) patients who received repair surgery for ATAAD. A total of 882 ATAAD patients who received emergency aortic dissection repair at our center from January 2015 to December 2019 were retrospectively screened in this study and divided into the dialysis group (n = 16) and the non-dialysis group (n = 866), depending on whether they required dialysis for preoperative ESRD. No significant difference of age, preoperative hemodynamics, organ ischemia conditions, operative variables as well as the 30-Day mortality and in-hospital complications was discovered between two groups. However, the survival rates and the proportion of late aortic event (sudden death and reoperation) free population at 1 and 3 years after surgery were significantly decreased in dialysis patients compared to non-dialysis patients. Our study indicated that the short-term surgical outcomes of ATAAD in dialysis patients were comparable to non-dialysis patient. However, the dialysis patients were associated with a worse long-term prognosis. Nature Publishing Group UK 2022-03-30 /pmc/articles/PMC8967816/ /pubmed/35354894 http://dx.doi.org/10.1038/s41598-022-09448-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Wang, Zhigang
Ge, Pingping
Lu, Lichong
Ge, Min
Chen, Cheng
Zhang, Lifang
Wang, Dongjin
Surgical outcomes of acute type A aortic dissection in dialysis patients: lessons learned from a single-center’s experience
title Surgical outcomes of acute type A aortic dissection in dialysis patients: lessons learned from a single-center’s experience
title_full Surgical outcomes of acute type A aortic dissection in dialysis patients: lessons learned from a single-center’s experience
title_fullStr Surgical outcomes of acute type A aortic dissection in dialysis patients: lessons learned from a single-center’s experience
title_full_unstemmed Surgical outcomes of acute type A aortic dissection in dialysis patients: lessons learned from a single-center’s experience
title_short Surgical outcomes of acute type A aortic dissection in dialysis patients: lessons learned from a single-center’s experience
title_sort surgical outcomes of acute type a aortic dissection in dialysis patients: lessons learned from a single-center’s experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967816/
https://www.ncbi.nlm.nih.gov/pubmed/35354894
http://dx.doi.org/10.1038/s41598-022-09448-7
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