NU-9 improves health of hSOD1(G93A) mouse upper motor neurons in vitro, especially in combination with riluzole or edaravone

Even though amyotrophic lateral sclerosis (ALS) is a disease of the upper and lower motor neurons, to date none of the compounds in clinical trials have been tested for improving the health of diseased upper motor neurons (UMNs). There is an urgent need to develop preclinical assays that include UMN...

Descripción completa

Detalles Bibliográficos
Autores principales: Genç, Barış, Gautam, Mukesh, Helmold, Benjamin R., Koçak, Nuran, Günay, Aksu, Goshu, Gashaw M., Silverman, Richard B., Hande Ozdinler, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967818/
https://www.ncbi.nlm.nih.gov/pubmed/35354901
http://dx.doi.org/10.1038/s41598-022-09332-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967818/
https://www.ncbi.nlm.nih.gov/pubmed/35354901
http://dx.doi.org/10.1038/s41598-022-09332-4

Ejemplares similares