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Genome-wide screening in the haploid system reveals Slc25a43 as a target gene of oxidative toxicity
Reactive oxygen species (ROS) are extensively assessed in physiological and pathological studies; however, the genes and mechanisms involved in antioxidant reactions are elusive. To address this knowledge gap, we used a forward genetic approach with mouse haploid embryonic stem cells (haESCs) to gen...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967898/ https://www.ncbi.nlm.nih.gov/pubmed/35354792 http://dx.doi.org/10.1038/s41419-022-04738-4 |