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Genome-wide screening in the haploid system reveals Slc25a43 as a target gene of oxidative toxicity

Reactive oxygen species (ROS) are extensively assessed in physiological and pathological studies; however, the genes and mechanisms involved in antioxidant reactions are elusive. To address this knowledge gap, we used a forward genetic approach with mouse haploid embryonic stem cells (haESCs) to gen...

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Detalles Bibliográficos
Autores principales: Zhang, Jinxin, Zhao, Yiding, Tian, Yaru, Geng, Mengyang, Liu, Yan, Zhang, Wenhao, Shuai, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967898/
https://www.ncbi.nlm.nih.gov/pubmed/35354792
http://dx.doi.org/10.1038/s41419-022-04738-4

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