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The impact of CCR8+ regulatory T cells on cytotoxic T cell function in human lung cancer

Regulatory T cells (Tregs) suppress the host immune response and maintain immune homeostasis. Tregs also promote cancer progression and are involved in resistance to immune checkpoint inhibitor treatments. Recent studies identified selective CCR8 expression on tumor-infiltrating Tregs; CCR8+ Tregs h...

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Detalles Bibliográficos
Autores principales: Haruna, Miya, Ueyama, Azumi, Yamamoto, Yoko, Hirata, Michinari, Goto, Kumiko, Yoshida, Hiroshi, Higuchi, Naoko, Yoshida, Tetsuya, Kidani, Yujiro, Nakamura, Yamami, Nagira, Morio, Kawashima, Atsunari, Iwahori, Kota, Shintani, Yasushi, Ohkura, Naganari, Wada, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967908/
https://www.ncbi.nlm.nih.gov/pubmed/35354899
http://dx.doi.org/10.1038/s41598-022-09458-5